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2008 T-C-U Horned Frogs Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 06:00 PM | at New Mexico | W, 26-3 | 1-0-0 |
| 09/06/2008 | 07:00 PM | Stephen F Austin | W, 67-7 | 2-0-0 |
| 09/13/2008 | 01:00 PM | Stanford | W, 31-14 | 3-0-0 |
| 09/20/2008 | 08:00 PM | at S-M-U | W, 48-7 | 4-0-0 |
| 09/27/2008 | 07:00 PM | at Oklahoma | L, 35-10 | 4-1-0 |
| 10/04/2008 | 06:00 PM | San Diego St | W, 41-7 | 5-1-0 |
| 10/11/2008 | 03:30 PM | at Colorado State | W, 13-7 | 6-1-0 |
| 10/16/2008 | 08:00 PM | B-Y-U | W, 32-7 | 7-1-0 |
| 10/25/2008 | 06:00 PM | Wyoming | W, 54-7 | 8-1-0 |
| 11/01/2008 | 08:00 PM | at U-N-L-V | W, 44-14 | 9-1-0 |
| 11/06/2008 | 08:00 PM | at Utah | L, 13-10 | 9-2-0 |
| 11/22/2008 | 03:30 PM | Air Force | W, 44-10 | 10-2-0 |
| 12/23/2008 | 08:00 PM | Boise State | W, 17-16 | 11-2-0 |
