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2008 Arizona Cardinals Schedule/Results
| Date | Time (ET) | Opponent | Result | Record |
| 09/07/2008 | 04:15 PM | at San Francisco | W, 23-13 | 1-0-0 |
| 09/14/2008 | 04:15 PM | Miami | W, 31-10 | 2-0-0 |
| 09/21/2008 | 01:00 PM | at Washington | L, 24-17 | 2-1-0 |
| 09/28/2008 | 01:00 PM | at NY Jets | L, 56-35 | 2-2-0 |
| 10/05/2008 | 04:15 PM | Buffalo | W, 41-17 | 3-2-0 |
| 10/12/2008 | 04:15 PM | Dallas | W, 30-24 | 4-2-0 |
| 10/26/2008 | 01:00 PM | at Carolina | L, 27-23 | 4-3-0 |
| 11/02/2008 | 01:00 PM | at St. Louis | W, 34-13 | 5-3-0 |
| 11/10/2008 | 08:30 PM | San Francisco | W, 29-24 | 6-3-0 |
| 11/16/2008 | 04:05 PM | at Seattle | ||
| 11/23/2008 | 04:15 PM | NY Giants | ||
| 11/27/2008 | 08:15 PM | at Philadelphia | ||
| 12/07/2008 | 04:15 PM | St. Louis | ||
| 12/14/2008 | 04:05 PM | Minnesota | ||
| 12/21/2008 | 01:00 PM | at New England | ||
| 12/28/2008 | 04:15 PM | Seattle |
